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Published on: 2002-09-17
Released on: 2002-09-17
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This series encompasses design, synthesis, application, and analytical methods (including clinical and in vitro) for the study of these critical interactions. As our understanding of the genome and proteome expands, general developments in the field of DNA sequence specific interaction are likely to play an increasingly important role. Accordingly, manuscripts have been solicited from experts covering a diverse range of fields, reflecting the cross-disciplinary and dynamic nature of the series.Volume 4 describes work on the modification of DNA by AT specific anticancer drugs, DNA alkylation events which involve metabolite generation, DNA sequence recognition by two selective binders, bulged DNA microenvironments as molecular targets, DNA sequence specific binding by short peptides and the analysis of DNA-protein interactions using DNase I footprinting methodology.Features include: • Expert contributors from the Biomedical world• Emerging areas of drug design and therapeutic applications• Nucleic acid-protein interactions• Color graphics of molecular modeling analyses• New and emerging methodologies Browse titles in books - ScienceDirect Please note that Internet Explorer version 8.x will not be supported as of January 1 2016. Please refer to this blog post for more information. TP53 - Wikipedia Identifiers BCC7 LFS1 P53 TRP53 tumor protein p53: External IDs: Genetically Related Diseases; basal cell carcinoma ... Racemic Single-Walled Carbon Nanotubes Exhibit Circular ... We have found that racemic mixtures of chiral single-walled nanotubes (SWNTs) wrapped with d(GT)20 DNA oligomer exhibit circular dichroism (CD). We attribute the CD ... DNA Nanotechnology for Cancer Therapy - thno.org Abstract. DNA nanotechnology is an emerging and exciting field and represents a forefront frontier for the biomedical field. The specificity of the interactions ... DNA - Wikipedia DNA is a long polymer made from repeating units called nucleotides. The structure of DNA is dynamic along its length being capable of coiling into tight loops and ... Mitochondrial DNA mutations and human disease Mitochondrial disorders are a group of clinically heterogeneous diseases commonly defined by a lack of cellular energy due to oxidative phosphorylation (OXPHOS Absence of Detectable HIV-1 Viremia after Treatment ... Case Report. An infant was born by spontaneous vaginal delivery at 35 weeks of gestation to a woman who had received no prenatal care. Rapid HIV-1 testing in the ... Spherical Nucleic Acids - Journal of the American Chemical ... A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This ... Real-Time PCR in Food Science: Current Technology and ... A principal consumer demand is a guarantee of the safety and quality of food. The presence of foodborne pathogens and their potential hazard the use of genetically ... CRISPR-Based Technologies for the Manipulation of ... Figure 2. Strategies for Improving the DNA Specificity of CRISPR-Based Agents (A) WT Cas9 variants have been shown to possess significant off-target activity.
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